KMID : 0367419930360040589
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Journal of Korean Pediatric Society 1993 Volume.36 No. 4 p.589 ~ p.595
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Recurrent Rhinocerebral Mucormycosis -A Case Report-
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Abstract
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A case of recurrent rhinocerebral mucormycosis that has occurred during an induction chemotherapy for acute megakaryocytic leukemia in a 10 year-old boy is reported. He had suffered from high fever, proptosis, right eye ball pain and necrotic
inflammation of hard palate during the chemotherapy of leukemia. CT scan of the paranasal sinus showed inflammatory change of right ethmoid and maxillary sinuses, and right orbital cystic mass which displaced medial rectus muscle. Pathologic
examination
of the inflammatory mass revealed mucormycosis with characteristic hyphae invading vessel walls. He was managed with 2 times of extensive debridement of necrotic tissue and currettage of cystic mass, and intravenous amphotericin-B for 80 days
with
apparent improvement. Seven months after discharge from the hospital, necrosis of posterior nasal septum and hard palate was noted for second time. It was managed again with 2 times of extensive debridement. Since this last operation he is on
follow-up
for 16 months uneventfully and is on therapy with low dose Ara-C in continuous remission
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KEYWORD
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